Genetic mapping of the mutation causing the arthrogryposis syndrome in Belgian Blue Cattle. A. Manhattan plot for the case–control GWAS study. B. Genotypes of 15 cases for a BTA10 segment centered around the most significant GWAS peak, and encompassing 324 SNP (from 70 to 90 Mb). Homozygous genotypes are shown in black or white, heterozygous genotypes in red. The presumed ancestral haplotype encompassing the mutation is underlined in yellow. The 2.2 Mb region of homozygosity shared by all cases is highlighted in red.