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Table 2 Colorectal cancer studies reporting on copy number alterations

From: Copy number alterations and allelic ratio in relation to recurrence of rectal cancer

  Studies   Origin of tissues Method Total CRC Rectum Colon TNM stage
      Figure 1 A # Figure 1 B # Figure 1 C #
1 Schlegel et al. 1995 Germany CGH yes 12 no (x) yes 12  
2 Ried et al. 1996 Germany CGH yes 16 yes 6 yes 10 2/3/(4)
3 Meijer et al. 1998 the Netherlands CGH yes 14 yes 7 yes 7  
4 Nakao et al. 1998 Japan CGH yes 9 no 0 yes 9 (1)/3
5 Paredes-Zaglul et al. 1998 USA CGH yes 9 yes 2 yes 7 (3)/4
6 Al-Mulla et al. 1999 UK CGH yes 12 no (x) no (x) 2/3
7 De Angelis et al. 1999 Norway CGH yes 45 no (x) no (x) 2/3/4
8 Georgiades et al. 1999 UK CGH yes 17 no (11) no (6) 1/2/3
9 Korn et al. 1999 USA CGH yes 6 no (0) yes 6 2/3/4
10 Aust et al. 2000 USA/Germany CGH yes 42 no (7) no (35) 1/2/3/4
11 Aragane et al. 2001 Japan CGH yes 30 no (x) no (x) 1/2/3/4
12 Chan et al. 2001 China/UK CGH yes 16 no (x) no (x) 2/3/4
13 De Angelis et al. 2001 Norway CGH yes 67 no (x) no (x) 1/2/3/4
14 Nakao et al. 2001 Japan CGH yes 35 no (13) no (22) 2/3/4
15 Rooney et al. 2001 USA CGH yes 29 no (4) no (25) 3
16 Hermsen et al. 2002 the Netherlands CGH yes 82 no (x) no (x) 1/(2)
17 Knösel et al. 2002 Germany CGH yes 15 no (x) no (x)  
18 Alcock et al. 2003 UK CGH yes 17 yes 6 yes 11  
19 Ghadimi et al. 2003 Germany CGH yes 50 yes 18 yes 32 1/2/3
20 He et al. 2003 China CGH yes 26 yes 14 yes 12 2/3/4
21 Leslie et al. 2003 UK CGH yes 50 no (21) no (29) 1/2/3
22 Bardi et al. 2004 Sweden/Denmark CGH yes 115 no (51) no (63) 1/2/3/4
23 Diep et al. 2004 Norway/Sweden CGH yes 10 no (x) no (x) (3)/4
24 Nakao et al. 2004 Spain aCGH yes 125 no (x) no (x) 1/2/3/4
25 Poeaim et al. 2005 Thailand CGH yes 40 no (10) no (30)  
26 Tanami et al. 2005 Japan CGH yes 20 yes 9 yes 11 (2)/(3)/4
27 Al-Mulla et al. 2006 UK/Kuwait CGH yes 70 no (47) no (18) 1/2
28 Grade et al. 2006 Germany CGH yes 21 yes 21 no 0 2/3
29 Grade et al. a 2007 Germany CGH yes 32 no 0 yes 32 2/3
30 Lips et al. 2007 the Netherlands SNPa yes 77 yes 77 no 0 1/2/3
31 Xiao et al. 2007 China CGH yes 24 yes 9 yes 15  
32 Lips et al. 2008 the Netherlands SNPa yes 32 yes 32 no 0 1/2/(3)
33 Grade et al. a 2009 Germany CGH yes 42 yes 42 no 0 1/2/3
34 Lagerstedt et al. 2010 Sweden aCGH yes 24 no (x) no (x) 1/2/3/4
35 Molinari et al. 2011 Italy aCGH yes 51 yes 51 no 0 1/2/3
36 Nakao et al. 2011 Japan aCGH yes 94 no (x) no (x) 1/2/3/4
37 Chen et al. b 2011/2012 USA aCGH yes 95 yes 95 no 0 2/3
38 Kodeda et al. 2012 Sweden aCGH yes 16 yes 16 no 0 1/2/3
39 Shi et al. 2012 China aCGH yes 8 yes 8 no 0  
40 Liang et al. 2013 China aCGH yes 48 yes 48 no 0 2/3/4
41 Zhou et al. 2013 China aCGH yes 16 yes 16 no 0 2/3
42 Doyen et al. 2014 France/Germany SNPa yes 80 yes 80 no 0 (1/2/3)
43 This study 2014 the Netherlands SNPa yes 112 yes 112 no 0 1/2/3
  Total   43   20   12   
  1. This table lists the published studies on CN alterations in rectal carcinomas used for comparisons with the present study (Nr. 43).
  2. Abbreviations: CGH, comparative genome hybridization; aCGH, arrayCGH; SNPa, SNP array; aUnclear if there is overlap with study Nr. 29 (Grade et al. [29]), bChen et al. published two papers based on the same patient cohort. Numbers in parentheses indicate the number of rectal or colon cancer patients included in the study, but for which results could not be distinguished between groups.