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Table 3 Differential allelic ratio groups between local recurrence and control

From: Copy number alterations and allelic ratio in relation to recurrence of rectal cancer

A) Local recurrence group Control group
Chr. p-value BH Retention Imbalance LOH Retention Imbalance LOH
1q 0.05 0.17 89% 11% 0% 45% 53% 2%
4q 0.05 0.17 78% 22% 0% 47% 22% 31%
7p 0.0005 0.015 100% 0% 0% 36% 62% 2%
7q 0.0007 0.015 100% 0% 0% 9% 13% 78%
10p 0.04 0.17 89% 11% 0% 53% 45% 2%
11p 0.04 0.17 89% 11% 0% 49% 42% 9%
13q 0.04 0.17 78% 11% 11% 27% 60% 13%
14q 0.017 0.17 78% 22% 0% 40% 22% 38%
15q 0.03 0.17 78% 22% 0% 29% 29% 42%
16q 0.06 0.18 89% 11% 0% 53% 36% 11%
17p 0.03 0.17 22% 33% 44% 9% 13% 78%
18q 0.05 0.17 11% 22% 67% 9% 13% 78%
22q 0.04 0.17 78% 11% 11% 33% 31% 36%
B) Local recurrence group Control group
Chr. p-value   Retention Imbalance LOH Retention Imbalance LOH
7 0.0025   9 0 0 19 25 1
13 0.0062   7 1 1 12 27 6
7 + 13 <0.0002   7 1 1 5 33 7
  1. A) For comparison of the local recurrence group and control group, chromosome arms are listed that showed significant allelic ratio groups with p-values <0.05 and adjusted p-values <0.2.
  2. Abbreviations: Chr, chromosome; B, p-value after using the Benjamin-Hochberg method for multiple testing correction.
  3. B) For chromosome 7, chromosome 13 and in combination, the numbers of patients within each ‘overall chromosome status’ group - defined as the most abundant allelic ratio group on the chromosome - are shown for both the local recurrence group (L) and the control group (C). Fisher’s exact test for count data was used to determine the statistical differences between analysis groups L and C.