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Figure 5 | BMC Genomics

Figure 5

From: Quantitative and multiplexed DNA methylation analysis using long-read single-molecule real-time bisulfite sequencing (SMRT-BS)

Figure 5

SMRT-BS utility and multiplexing. (A) Heat map of SMRT-BS methylation quantitation results for four CpG island amplicons [AFAP1 (798 bp), CEBPA (702 bp and 866 bp), CDKN2A (770 bp)] and 30 hematological malignancy cell lines. CDKN2A deletion is illustrated by grey bars. (B) SMRT-BS methylation results of 79 CpG sites for the K562 cell line were compared to available RRBS data from the ENCODE project [31], revealing a correlation of 0.900.

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BMC Genomics

ISSN: 1471-2164

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