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Table 1 Methylated motifs detected for H. pylori UM032

From: The complete methylome of Helicobacter pylori UM032

Type of RM system Motifs a Type of modification No. detected d No. in genome % detected Locus tag Nomenclature
I GANNNNNNNTAYG m6A 653 653 100.00 K747_03505 M.HpyUM032XII
IIP TCGA m6A 526 526 100.00 K747_09985 M.HpyUM032XVII
IIP CA TG m6A 14370 14370 100.00 K747_04980 M.HpyUM032I
IIP ACNGT m4C 1005 1104 91.03 K747_10995 M.HpyUM032II
IIP GA TC m6A 10172 10172 100.00 K747_09245 M.HpyUM032III
IIP GANTC m6A 5388 5388 100.00 K747_12490 M.HpyUM032IV
IIP CCGG m4C 3396 3416 99.41 K747_10000 M.HpyUM032IX
IIP TCNGA m6A 2530 2532 99.92 K747_05140 M.HpyUM032V
IIP ATTAAT m6A 857 874 98.05 K747_10980 M.HpyUM032VII
IIP TGCA m6A 11260 11270 99.91 K747_12120 M.HpyUM032VIII
IIS GAGG m6A 4578 4579 99.98 K747_08850 M2.HpyUM032VI
IIS CCATC m6A 2255 2255 100.00 K747_03690 M1.HpyUM032X
IIP GC GCe m5C 774 2396 32.30 K747_05430 M.HpyUM032XV
IIG CYANNNNNNNTRGb m6A 2319 2320 99.96 K747_03825 HpyUM032XIII
IIG GAAAGb m6A 2514 4955 50.74 K747_03595 HpyUM032XIV
IIP GTNNAC m6A 528 528 100.00 K747_06370 M.HpyUM032XI
IIP GT AC m6A 174 174 100.00 K747_06575 M.HpyUM032XVIII
I CCANNNNNNTCb,c m6A - - - K747_10905 M.HpyUM032XVI
  1. aThe methylated base within the motif is in bold while the methylated base in the complementary strand is italic.
  2. bNovel recognition sequences.
  3. cActivity identified only after cloning. No methylation activity was observed in H. pylori UM032.
  4. dThe total number includes motifs occurring on the “+” and “–” strands.
  5. eLow percentage detected, due to m5C modification.