In vivo validation of the Xenopus NRSE screen. Four F-box ubiquitin ligases identified in the NRSE screen are expressed in the neuronal tissues of X. tropicalis.
A. The genomic localization of the genes with respect to NRSE motifs and B. their mRNA expression hybridization during X. tropicalis development. Gastrula embryos are ventral view with dorsal to the top. Neurula embryos are dorso-lateral view with anterior to the right. Early tailbud embryos are dorsal view with anterior to the right. Tailbud heads are lateral view with anterior to the right. The arrows point the direction of genes. Intervening genes are in turquoise. Cartoons are not to scale.