Figure 1
From: Genomic landscape of rat strain and substrain variation
‘Repression’ of genes and exons containing high impact SNVs. (a) Genome-wide average FPKM ± SEM across all tissues compared to the average FPKM of genes containing high impact SNVs for 12 tissues. Genes containing high impact SNVs are significantly lower expressed (Non-parametric ANOVA; p < 0.0001). (b) The average Percentage Spliced In (PSI) ± SEM across the transcriptome was compared to the average PSI of exons containing high impact SNVs for 12 tissues. Exons containing high impact SNVs are significantly more spliced out/not used (Non-parametric ANOVA; P < 0.0001).