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Table 2 Selected phenotypic and genomic antibiotic resistance profiles in strains of ST772-MRSA-V

From: Single-molecule sequencing reveals the molecular basis of multidrug-resistance in ST772 methicillin-resistant Staphylococcus aureus

Antibiotic Phenotype (MIC μg/L)   Resistance Genes and Mutations in ST772-MRSA-V
  DAR4145   DAR4145 07-17048 KT/Y21 118 120 333 3957 3989 LVP2 VH60
Oxacillin R (≥4) mecA (M) + + + + + + + + + +
blaZ (M) + + + + + + + + + +
blaZ (P) + - + + +/− - - + + +
Gentamicin R (≥16) aacA-aphD (M) + + + - + + + + + +
aphA-III, sat4, aadE(p) (P) + + + +/− + - - + + +
Trimethoprim/Sulfamethoxazole R (≥320) dfrA (C) + + + + + + + + + +
dfrG (C) + - - - + + - + + +
dfrG (M) + + + + - - + - - -
Ciprofloxacin Levofloxacin Moxifloxacin R (4) R (4) I (1) norA/norB (C) + + + + + + + + + +
grlA (S80T/F) + + + + + + + + + +
gyrA (S84L) + + + + + + + + + +
Tetracyline S (≤1) tet(38) (C) + + + + + + + + + +
Erythromicin Clindamycin I (1) S ( ≤0.25) msrA-mphC (P) + + + + + - - + + +
  1. (R = Resistant, I = Intermediate, S = Susceptible,C = Chromosomal, M = Mobile Genetic Element, P = Integrated Resistance Plasmid, + = present, − = absent, p = partial, +/− = partial or truncated).