The gene ontology category of each group at indicated time points. The Gene Ontology analysis was performed by BiNGO plugged-in Cytoscape. The Biological Processes (BP), Molecular Function MF and Cellular Components CC terms were involved. To include only significant results, the FDR threshold was set to 0.05. The top 20 terms were selected, and represented as bar plots with gene number involved in these GO terms (with reference to the upper y-axis). Moreover, the corrected p values were also obtained as indicated by the yellow dotted line, which had been transformed into log10 with reference to the lower y-axis. The red dashed line indicated the threshold of adjusted p values [−log10 (0.05)].