Fig. 8
From: DNA methylation and gene expression in Mimulus guttatus
DNA methylation around transcriptional start sites. Around gene start sites, and persisting into the first 500 base pairs of the gene body, we observe a significant drop in DNA methylation. For CG (p-value = 6.45 × 10−55), CHG (p = 3.38 × 10−100), and CHH (p = 4.61 × 10−308) methylation was significantly reduced in the first 500bp of the gene relative to the up-stream regions. Both CG (p = 3.55 × 10−138) and CHG (p = 4.04 × 10−11) methylation then significantly increases over the next 500 bp, while for CHH it continued to decline (p = 8.93 × 10−10)