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Table 2 Ten most significant gene sets enriched in PC1 correlating genes. Tables a and b are subsets of gene sets that were significantly (FDR q-value < 1 %) enriched in PC1 correlating genes by PC-GSEA (for full data, see Additional file 10: Table S7). (a) Gene sets in positively correlated genes, which were upregulated in SGs, and (b) gene sets in negatively correlated genes, which were upregulated in KCs and HaCaTs. SIZE is number of genes belonging the gene set. NES is normalized enrichment score

From: Gene expression analysis of skin grafts and cultured keratinocytes using synthetic RNA normalization reveals insights into differentiation and growth control

Name SIZE NES FDR q-val
(a)    
PEREZ_TP53_AND_TP63_TARGETS 198 2.967 0
SMID_BREAST_CANCER_NORMAL_LIKE_UP 449 2.908 0
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_DN 31 2.774 0
KRAS.LUNG_UP.V1_DN 128 2.774 0
ABATES_COLORECTAL_ADENOMA_DN 248 2.760 0
WU_SILENCED_BY_METHYLATION_IN_BLADDER_CANCER 53 2.758 0
PEREZ_TP63_TARGETS 334 2.742 0
WINNEPENNINCKX_MELANOMA_METASTASIS_DN 46 2.735 0
KEGG_ASTHMA 23 2.689 0
KEGG_ALLOGRAFT_REJECTION 33 2.663 0
(b)    
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 172 3.060 0
MOOTHA_VOXPHOS 86 3.038 0
WONG_EMBRYONIC_STEM_CELL_CORE 332 3.028 0
REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTH ESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_ BY_UNCOUPLING_PROTEINS_ 81 3.016 0
FOURNIER_ACINAR_DEVELOPMENT_LATE_2 276 3.005 0
KEGG_OXIDATIVE_PHOSPHORYLATION 111 2.954 0
PENG_LEUCINE_DEPRIVATION_DN 186 2.947 0
GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN 199 2.947 0
WONG_MITOCHONDRIA_GENE_MODULE 216 2.943 0
REACTOME_RESPIRATORY_ELECTRON_TRANSPORT 65 2.924 0