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Fig. 4 | BMC Genomics

Fig. 4

From: The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling

Fig. 4

Immunohistochemical staining of proteins elevated in cardiac muscle. a Examples of eight proteins related to muscle contraction (MYH6, MYL4, MYL7, ACTC1, TNNI3, TNNT2, MYBPC3 and CACNA1C). CACNA1C was distinctly stained in sarcolemma and endothelial cells. b Examples of four proteins related to homeostasis and regeneration/repair, with NPPA displaying granular cytoplasmic expression, AKAP6 observed in nuclear membranes of cardiomyocytes, NES restricted to endothelial cells and BVES distinctly stained in sarcolemma. c Examples of eight proteins specific for intercalated discs (ATP1A3, CDH2, MYZAP, PKP2, ART3, FILIP1, POPDC2 and RAB9B). d Examples of two proteins with unknown function in cardiac muscle (SBK2 and SHD)

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