Fig. 5
From: Drosophila anti-nematode and antibacterial immune regulators revealed by RNA-Seq
Differential gene expression analysis using DESeq and GLM analysis to compare the different infection types. a Filtered list of genes that are common between all three infection types (p < 0.05); b Filtered list of genes that are common between the Axenic Heterorhabditis vs. Symbiotic Heterorhabditis and Axenic Heterorhabditis vs. Photorhabdus comparisons; c Filtered list of genes that are common between the Symbiotic Heterorhabditis vs. Photorhabdus and Axenic Heterorhabditis vs. Photorhabdus comparisons. The figure contains Drosophila genes with significantly altered expression upon infection of adult flies with the nematodes and their associated bacteria (separately or together), and their corresponding adjusted p-values for the two models used: one to determine the common genes between Heterorhabditis (Axenic/Symbiotic) infections and Photorhabdus infections, and a second to determine the common genes between Axenic Heterorhabditis infection and Photorhabdus infection after adjusting for the two time-points. Selected genes included those that appeared in all three comparisons. Red: LFC ≥ 2-fold downregulation; Yellow: LFC ≤ 2-fold downregulation and Green: LFC ≥ 2-fold upregulation