Fig. 6
From: Drosophila anti-nematode and antibacterial immune regulators revealed by RNA-Seq
Expression of immune-related genes in Drosophila flies infected by Heterorhabditis nematodes or their Photorhabdus bacteria. a Heat map showing immune-related genes that are differentially expressed by Heterorhabditis axenic nematodes, symbiotic nematodes and Photorhabdus bacteria at 12 h and 30 h post-infection. Genes selected from the Gene Ontology (GO) analysis correspond to the immune response category and have a positive expression level as an indication of their upregulation upon infection with the pathogens. Selected genes were assigned to the following immune pathways or immune-related groups: TNF, JAK/STAT, TOLL, JNK, IMD and VEGF pathways; immune induced molecules, PGRPs with unknown function, hematopoiesis, scavenger receptors, lysozymes and others. GO immune response categories identified in flies infected by b Heterorhabditis axenic nematodes, c Heterorhabditis symbiotic nematodes, or d Photorhabdus bacteria at 30 h post-infection. The Y-axis corresponds to the number of genes for each GO category and their relative level of expression (upregulation or down-regulation). All genes have a fold-change higher than 2 (Log Fold-Change = 0.58 corresponds to 2-fold-change difference)