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Table 4 Number of co-regulated genes in H2O2-exposed control and ΔatfA cultures

From: Core oxidative stress response in Aspergillus nidulans

Transcriptional changesa

Strain

THS30.3 control strain

TNJ 92.4 ΔatfA strain

Up-regulated genes

Down-regulated genes

Up- or down-regulated genes

Up-regulated genes

Down-regulated genes

Up- or down-regulated genes

l-H2O2

153

317

470

354

329

683

h-H2O2

799

789

1588

863

835

1698

at least in one of them

833

835

1668

1050

999

2049

in both of themb

119 (0.78)

271 (0.85)

390 (0.83)

167* (0.47)

165* (0.50)

332* (0.49)

  1. *The number of genes regulated in both H2O2 experiments in respect to the number of genes regulated by l-H2O2 treatment is significantly smaller in the ΔatfA mutant than in the control strain according to the Fisher’s exact test (p < 0.05)
  2. aNumbers of genes with at least two-fold increase or decrease in their transcriptions under the specified stress conditions are presented for both the control and the ΔatfA strains. Stressor concentrations are presented in footnotes to Table 2
  3. bNumbers of genes regulated in both experiments are given. The number of genes regulated in both experiment/number of genes regulated in the presence of l-H2O2 ratios are also given in parenthesis