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Fig. 1 | BMC Genomics

Fig. 1

From: Identification of sequences common to more than one therapeutic target to treat complex diseases: simulating the high variance in sequence interactivity evolved to modulate robust phenotypes

Fig. 1

Bias of dinucleotide frequencies observed in species of different complexity. Mutational biases CA/AC (a), AT/TA (b), AG/GA (c), GC/CG (d). Examples of sequences and their frequencies in human cDNA comprising a random collection of low-frequency (e) or high-frequency dinucleotides are shown (f). Horizontal lines represent ratio 1:1, i.e., no bias. Error bars are contained in data points and represent 95 % confidence intervals (binomial distributions) in comparison with random expectations. Ec (Escherichia coli CFT073), At (Arabidopsis thaliana), Ce (Caenorhabditis elegans), Dm (Drosophila melanogaster), Mm (Mus musculus), Hs (Homo sapiens)

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