Table 1 Antisense gapmer oligonucleotides that exclusively demonstrate reverse complementarity to multiple cDNAs related to particular disorders. All nucleotides are linked by phosphorothioate linkages *, and conformationally restricted nucleotide monomers, such as tricycle-DNA, LNAs and MOEs, are preceded by +. Additional sequences can be found in Table S1 and will be updated at www.wikisequences.org

Cancer

+T*+T*+G*A*T*G*G*G*G*A*A*C*T*+T*+G*+G

ABL1,BLK,FGR,HCK.

+G*+C*+C*A*A*G*C*C*A*A*A*+G*+T*+C

ACVR2B,ARAF,CHECK1,FGR.

+A*+G*+G*T*C*C*A*G*T*T*T*+C*+T*+G

ATR,MKI67,PNK3.

+T*+G*+T*C*A*G*C*T*G*T*C*+A*+T*+T

BCL2,HIF2,PSMA6.

+T*+T*+G*G*T*T*T*C*C*T*T*+T*+G*+C

BIRC5,HK2,USP34.

+G*+G*+C*C*A*G*G*C*C*A*A*A*+G*+T*+C

CAMK2A,CDK4,CDK16,FIP1L1,

HCK,IRAK1,PDGFRA.

+A*+C*+C*A*G*C*T*G*C*T*T*G*+A*+A*+G

CCNE2,FGR1,FGR3,FGR4.

+G*+G*+C*C*A*G*G*C*C*A*A*A*G*+T*+C*+A

CDK4,CDK16,FIP1L1,HCK,MAPK(1&9).

+G*+C*+C*A*T*C*C*A*C*T*T*+C*+A*+C

C-KIT,C-MET,CSF1R,FGFR1,FGFR3,

FGFR4,FIP1L1,MST1R,PDGFRA.

+T*+T*+G*C*G*G*G*C*A*G*C*C*+A*+G*+G

CSK,EPHB2,FGR3,FGR4,TNK2,RIPK4.

+G*+T*+T*A*C*A*A*G*C*A*T*+C*+A*+T

DOCK7,TGFB2,USP14.

+A*+G*+C*C*A*C*T*G*G*A*T*+G*+T*+G

E2F1,FGR1,FGR3,FGR4,HSPA12A.

+T*+G*+T*G*A*T*A*C*T*T*T*+C*+T*+G

EBAG9,MCL1,PTGS2,TMED7-TICAM2.

+A*+C*+A*T*C*A*C*T*C*T*G*G*T*G*+G*+G*+T

EGFR,FGFR1,HER2.

+C*+A*+C*C*T*G*G*T*A*G*G*C*+G*+C*+A

FGFR1,FGFR4,TERT.

+T*+C*+A*C*T*G*T*A*C*A*C*+C*+T*+T

FGR1,FGR3,GRB7.

+C*+A*+C*C*T*G*G*T*A*G*G*C*+G*+C*+A

FGR1,FGR4,TERT.

Immunological diseases

+C*+C*+A*A*C*C*T*T*C*A*+C*+A*+C

CARD9,IL7R,RPL5.

+T*+C*+T*C*C*T*T*C*C*T*C*T*G*+C*+T*+T

KRT17,NLRP1.

+C*+C*+G*T*G*G*G*T*C*C*C*T*G*+G*+C*+A

ILR6,TLR9.