Fig. 4

The miR-342-3p eQTL. a. Expression of miR-342-3p in CC founders (a) and preCC mice (b) as a function of founder haplotype at the eQTL on chromosome 12. CC founder miRNA expression was measured by microarray while preCC miRNA expression was measured by qRT-PCR and data for the latter are presented as −1*DeltaCq (normalized to miR-17*). c. Phylogeny of CC founder strains based on SNP data for the region on Chr 12 containing the miR-342-3p eQTL. Bootstrap values were greater than or equal to 96 (out of 100) for each branch of tree.The red line denotes the branch that contains the putative causal variant