Table 1 Transcription factors enriched in the set of TFBS-ID close to the TSS of known human genes. “TF” refers to the name of the transcription factor; “Number of TFBS” refers to the number of binding sites for the respective TF within the TFBS-ID set; “p-value” refers to the degree of significance for the respective TF enrichment with the final TFBS set against all TFBS near genes.
From: Populational landscape of INDELs affecting transcription factor-binding sites in humans
TF | 5Kbp upstream | 5Kbp flanking | ||
|---|---|---|---|---|
N | p-value | N | p-value | |
Pol2 | 1818 | <10-4 | 4505 | <10-4 |
CTCF | 1368 | <10-4 | 1982 | <10-4 |
TBP | 879 | <10-4 | 1941 | <10-4 |
HA-E2F1 | 684 | <10-4 | 1877 | <10-4 |
NFKB | 666 | <10-4 | 1244 | <10-4 |
ZNF263 | 606 | <10-4 | 1238 | <10-4 |
TCF4 | 370 | <10-4 | 623 | <10-4 |
AP-2alpha | 237 | <10-4 | 475 | <10-4 |
Pol2(b) | 364 | 0,002 | 802 | <10-4 |
YY1_(C-20) | 580 | 0,097 | 1134 | <10-4 |
Max | 511 | 0,162 | 962 | <10-4 |
CEBPB | 721 | 0,217 | 929 | <10-4 |
Pol2-4H8 | 1264 | 0,246 | 2532 | <10-4 |
SP1 | 534 | 0,315 | 1090 | <10-4 |
TAF1 | 905 | 0,577 | 2120 | <10-4 |
USF-1 | 538 | 0,668 | 872 | <10-4 |
CCNT2 | 385 | 0,752 | 915 | <10-4 |
ELF1_(SC-631) | 693 | 0,993 | 1517 | <10-4 |
c-Myc | 613 | 0,998 | 1164 | <10-4 |
HEY1 | 827 | 1,000 | 1523 | <10-4 |
Sin3Ak-20 | 505 | 1,000 | 1129 | <10-4 |
E2F6_(H-50) | 524 | 1,000 | 1026 | <10-4 |
YY1 | 434 | 1,000 | 872 | <10-4 |
GATA-1 | 432 | <10-4 | 747 | 1,000 |
AP-2gamma | 351 | <10-4 | 684 | 1,000 |
GATA-2 | 373 | <10-4 | 546 | 1,000 |
ELK4 | 155 | <10-4 | 450 | 1,000 |
KAP1 | 280 | <10-4 | 444 | 1,000 |
STAT1 | 202 | <10-4 | 359 | 1,000 |
ZZZ3 | 28 | <10-4 | 41 | 1,000 |
SETDB1 | 193 | <10-4 | 246 | 0,494 |
TR4 | 97 | 0,001 | 225 | 1,000 |
E2F4 | 216 | 0,001 | 506 | 1,000 |
eGFP-GATA2 | 95 | 0,004 | 127 | 1,000 |