Distinct polymer physics principles govern chromatin dynamics in mouse and Drosophila topological domains

BMC Genomics

Table 2 Fitting the unconstrained model on Drosophila Hi-C data^a

Chromosome	Parameters	Active D1	Black D2	PcG D3	Centromeric D4
	K *10⁹	0.852	1.487	1.340	2.405
Chr2L	S (kb)	4.150	4.918	4.849	5.296
	L (nm/kb)	10.81	10.56	10.6	10,32
	K *10⁹	0.847	1.471	1.122	2.699
Chr2R	S (kb)	4.147	4.925	4.552	5.292
	L (nm/kb)	10.76	10.57	10.71	9.99
	K *10⁹	0.808	1.383	1.232	2.684
Chr3L	S (kb)	4.090	4.881	4.873	5.382
	L (nm/kb)	10.80	10.55	10.62	10.06
	K *10⁹	0.857	1.548	1.324
Chr3R	S (kb)	4.132	4.95	4.773
	L (nm/kb)	10.80	10.59	10.64
	K *10⁹				1.303
Chr4	S (kb)				4.55
	L (nm/kb)				10.67

Median values of 3 best-fit parameters obtained on the autosomal chromosomes in each type of TADs
^aHi-C samples were prepared from unsexed flies, and therefore the X chromosome was not analysed since, in males, this chromosome undergoes dosage compensation that largely affects its epigenetic features

ISSN: 1471-2164