Table 1 Genes selected for functional analysis
Gene | Fold change | FDR | biological function | Brain Enrichmenta |
|---|---|---|---|---|
DopR | −0.52 | 0.028 | activation of adenylate cyclase activity | 123 |
CG11155 | −0.37 | 0.108 | ion transport | 12 |
sug | −0.82 | 0 | positive and negative regulation of transcription | Eye |
sif | −0.58 | 0.015 | regulation of synapse structure and activity, synaptic transmission | 25 |
Thor | −0.36 | 0.09 | negative regulation of translational initiation, antibacterial humoral response | NA |
Nf1 | −0.51 | 0.022 | locomotor rhythm, cAMP-mediated signalling, regulation of Ras protein signal transduction | 17 |
pho | −0.39 | 0.075 | negative regulation of gene expression | 1.6 |
CalX | −0.38 | 0.077 | Phototransduction | Eye |
nrv1 | −0.34 | 0.105 | potassium ion transport, sodium ion transport | Eye |
modifier of mdg4 | −0.42 | 0.044 | regulation of apoptosis, regulation of chromatin assembly or disassembly | 2.6 |
Hr38 | 0.8 | 0 | phagocytosis, engulfment | 24 |
Fmr1 | 0.5 | 0.018 | circadian rhythm, brain development, neurotransmitter secretion, synaptic transmission | 4.3 |
CG7589 | 0.41 | 0.07 | phagocytosis, engulfment | Eye |
CG11597 | 0.6 | 0.013 | protein amino acid dephosophorylation | 2.1 |
CG2051b | 0.44 | 0.055 | histone acetylation; chromatin silencing at telomere | 0.6 |
Nipped-Ab | −0.46 | 0.034 | Signalling, transcriptional co-activator. A key component of both the SAGA and Tip60 (NuA4) chromatin-modifying complexes. | 1.9 |
trithoraxb | −0.41 | 0.062 | histone methylation; histone H3-K4 methylation | 4.1 |
PScb | 0.48 | 0.035 | chromatin remodelling | 1.8 |
nejireb | −0.42 | 0.059 | histone acetyltransferase activity, H3-K27 specific, H3-K18 specific |  |
Sirt6b | 0.36 | 0.082 | Predicated histone deacetylation activity, determination of adult life span | 0.6 |
Kr-h1b | −0.37 | 0.089 | transcription factor activity | 2.3 |
Su(var)3-9b | 0.48 | 0.024 | Histone methyltransferase | 2.3 |