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Table 1 Comparison of the venom-gland transcriptomes and the venom proteomes of king cobra (Ophiophagus hannah, Oh) from Malaysia (Seremban) and Indonesia (Bali)

From: Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah)

 

Venom-gland transcriptome

Venom Proteome

 

Malaysian Oh (Current study)

Balinese Oh (Vonk et al., 2013)

Malaysian Oh (Current study)

Balinese Oh (Vonk et al., 2013)

Toxin Family

aTranscript (abundance in %)

bTranscript detected

cRelative abundance of toxin in % (number of subtype)

dRelative presence of toxin in % (number of subtype)

3FTXs

84.95

√

43.0 (13)

41.1 (30)

SVMP

3.68

√

24.4 (12)

24.7 (18)

PLA2

2.16

√

4.0 (1)

5.5 (4)

CRISP

2.12

√

8.7 (1)

6.8 (5)

KUNs

1.84

√

1.0 (1)

4.1 (3)

LAAO

1.47

√

5.7 (2)

1.4 (1)

CVF

0.63

√

2.8 (4)

5.5 (4)

Vespryn

0.58

√

5.7 (1)

1.4 (1)

IGF

0.52

√

-

-

NP

0.48

√

-

1.4 (1)

SVSP

0.47

√

0.7 (1)

4.1 (3)

Cystatin

0.25

√

0.7 (1)

-

PDE

0.22

√

1.1 (2)

1.4 (1)

NGF

0.20

√

0.8 (1)

-

AChE

0.14

√

0.1 (1)

-

Neprilysin

0.11

√

0.7 (2)

-

Hyaluronidase

0.07

-

-

-

PLB

0.07

√

0.2 (1)

-

Waprin

0.06

√

-

-

DPP IV

0.02

-

-

-

5' Nucleotidase

0.02

-

0.4 (1)

-

CTL

0.01

√

-

-

VEGF

0.01

√

-

2.7 (2)

Total

100

 

100.0 (45)

100.0 (73)

  1. aThe relative abundance of a particular transcript was expressed in percentage of total FPKM of all toxins. Values shown are percentages sorted according to toxin gene families
  2. bThe detection of transcript sorted according to toxin gene family. Exact quantitative values were not provided in the original report. √ indicates detection
  3. cThe relative abundance of a particular toxin was expressed in percentage of total mean spectral intensities of all toxins (adjusted to gel intensity). Values shown are percentages sorted according to toxin protein families. The numbers of subtype within each family are indicated in brackets
  4. dThe relative ‘presence’ of a particular toxin was expressed in percentage of the total number of all toxin subtypes (n = 73). Values shown are percentages sorted according to toxin protein families. The numbers of subtype within each family are indicated in brackets