Integrative analysis of the microRNA-mRNA response to radiochemotherapy in primary head and neck squamous cell carcinoma cells

Table 1 Characteristics of primary HNSCC cell cultures

Case	HN1957	HN2092
Gender of patient	f	m
Age at diagnosis, years	85	73
Tumor site	left maxilla / left nasal floor	right floor of mouth
TNM	n.a.	pT4pN0
HPV-status	negative	negative
EBV-status	negative	n.a.
P53-status	mutated	wild type
Radiosensitivity
α (+/-SD)	0.094 (+/− 0.022)*	0.614 (+/− 0.019)*
β (+/-SD)	0.038 (+/− 0.004)**	0.021 (+/− 0.003)**
SF2	0.71	0.27
Cell type	epithelial	epithelial

n.a. Not available, SD Standard deviation, SF2 Surviving fraction at 2 Gy
*ttest of α values results in significant difference between HN1957 and HN2092 (p < 0.05)
**ttest of β values results in significant difference between HN1957 and HN2092 (p < 0.05)

ISSN: 1471-2164