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Table 1 Summary of the gene-set enrichment analysis for pathways with FDR < 0.2

From: Using genome-wide associations to identify metabolic pathways involved in maize aflatoxin accumulation resistance

MaizeCyc ID

PW Name

NES

p

q

Genesa

PWY-735

jasmonic acid biosynthesis

4.55

2.63E-6

0.001

28

PWY-6124

inosine-5′-phosphate biosynthesis II

3.18

0.0007

0.109

8

PWY-5136

fatty acid β-oxidation II (core pathway)

2.85

0.0022

0.163

25

ARGASEDEG-PWY

arginine degradation I (arginase pathway)

2.79

0.0026

0.163

14

FOLSYN-PWY-1

superpathway of tetrahydrofolate biosynthesis

2.68

0.0037

0.163

15

PWY-3001

isoleucine biosynthesis I

2.64

0.0041

0.163

65

SULFATE-CYS-PWY

superpathway of sulfate assimilation and cysteine biosynthesis

2.61

0.0046

0.163

24

BRANCHED-CHAIN-AA-SYN-PWY

superpathway of leucine, valine, and isoleucine biosynthesis

2.55

0.0054

0.163

38

PWY-5409

divinyl ether biosynthesis II

2.53

0.0056

0.163

7

PWY-6435

4-hydroxybenzoate biosynthesis V

2.53

0.0057

0.163

20

PWY-3461

tyrosine biosynthesis II

2.50

0.0063

0.163

7

PWY-561

superpathway of glyoxylate cycle

2.46

0.0069

0.163

59

PWY-6040

chlorogenic acid biosynthesis II

2.43

0.0076

0.163

5

PWY-4221-1

superpathway of pantothenate and coenzyme A biosynthesis II

2.43

0.0076

0.163

43

THRESYN-PWY

threonine biosynthesis

2.40

0.0083

0.165

41

LEUSYN-PWY

leucine biosynthesis

2.37

0.0090

0.167

21

PWY-5481

pyruvate fermentation to lactate

2.33

0.0098

0.172

8

  1. ID identifier, PW pathway, NES normalized enrichment score
  2. aThe number of genes that were mapped to a pathway and contributed to the enrichment score calculation