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Table 1 Transcription factor binding site enrichment in promoter regions of the top 5 % complex I co-expressing nuclear genes

From: Transcriptome analysis of complex I-deficient patients reveals distinct expression programs for subunits and assembly factors of the oxidative phosphorylation system

 

  1. Background: all human genes. Listed are all individually significantly enriched TFs (i.e. without correcting for multiple testing; Fisher’s exact P < 0.05). TFs with Benjamini-Hochberg-corrected Fisher’s exact P < 0.05 are shaded in grey. TFs with a known role in OXPHOS biogenesis are in bold See Additional file 6: Table S5 for detailed results