Fig. 1
From: The idiopathic preterm delivery methylation profile in umbilical cord blood DNA
Neonatal sex chromosomal variations detected through quality control of umbilical cord blood Illumina 450Â K data. a Multi-dimensional scaling (MDS) plot on neonatal sex on the top 1000 methylation variable positions between male (in red) and female (in green) samples; T4-Klinefilter neonate. b Validation of the X-chromosomal gain of neonate T4 by QF-PCR supporting the diagnosis of Klinefelter Syndrome: Markers DXS6803 (Xq21.31), HPRT (Xq26.2), TAF9L (Xq21.1), DXS1187 (Xq26.2) are specific for the X chromosome. Markers SRY (Yp11.31) and AMEL (Xp22.22)/ (Yp11.2) are specific for the Y chromosome