Fig. 1

A schematic of some of the features used in the model. The alternating blue and green regions denote the 13 consecutive windows around the target site (shown in red), where various thermodynamic and sequence features are computed. The seed alignment pattern is computed by considering the mRNA nucleotides that are aligned with nucleotides from index 1 to 8 from the 5’ end of the miRNA. The alignment is represented by a vector of 1 (match), 2 (mismatch), 3 (gap), and 4 (GU wobble). The relative position of the target site within an mRNA region and the length of the target site are also used as features