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Table 3 Top gene ontology clusters of SDE genes between liver samples from juvenile and laying hens

From: Transcriptome profile of liver at different physiological stages reveals potential mode for lipid metabolism in laying hens

Categorya Term ID Term Genes P-value
GOTERM_BP_FAT GO:0016125 Sterol metabolic process APOB, APOA1, HMGCR, CYP7A1, LCAT, INSIG1, FDPS, LSS, SC4MOL, VLDLR, DHCR24 1.68E-07
GOTERM_BP_FAT GO:0008203 Cholesterol metabolic process APOB, APOA1, HMGCR, CYP7A1, LCAT, INSIG1, FDPS, LSS, VLDLR, DHCR24 7.58E-07
SP_PIR_KEYWORDS   Lipid metabolism FAR1, APOB, APOA1, LCAT, INSIG1, ACSBG2, AACS, VLDLR 1.15E-05
GOTERM_BP_FAT GO:0008202 Steroid metabolic process OSBPL3, HMGCR, FDPS, LSS, SC4MOL, APOB, APOA1, LCAT, CYP7A1, INSIG1, OSBPL10, VLDLR, DHCR24 8.40E-05
SP_PIR_KEYWORDS   Cholesterol metabolism APOB, APOA1, LCAT, INSIG1, VLDLR 7.97E-04
GOTERM_BP_FAT GO:0006869 Lipid transport APOB, TPRXL, APOA1, PPARG, ANXA1, ATP11A, CETP, VTG2, ATP8B3, VLDLR 8.29E-04
GOTERM_BP_FAT GO:0016126 Sterol biosynthetic process HMGCR, FDPS, LSS, SC4MOL, DHCR24 8.92E-04
SP_PIR_KEYWORDS   Steroid metabolism APOB, APOA1, LCAT, INSIG1, VLDLR 0.00150
GOTERM_CC_FAT GO:0032994 Protein-lipid complex APOB, APOA1, CETP, APOVLDLII, VLDLR 0.00155
GOTERM_CC_FAT GO:0034358 Plasma lipoprotein particle APOB, APOA1, CETP, APOVLDLII, VLDLR 0.00155
GOTERM_BP_FAT GO:0010876 Lipid localization APOB, TPRXL, APOA1, PPARG, ANXA1, ATP11A, CETP, VTG2, ATP8B3, VLDLR 0.00167
GOTERM_BP_FAT GO:0006695 Cholesterol biosynthetic process HMGCR, FDPS, LSS, DHCR24 0.00432
SP_PIR_KEYWORDS   VLDL APOB, APOVLDLII, VLDLR 0.02855
GOTERM_CC_FAT GO:0034361 Very-low-density lipoprotein particle APOB, APOVLDLII, VLDLR 0.03533
GOTERM_CC_FAT GO:0034385 Triglyceride-rich lipoprotein particle APOB, APOVLDLII, VLDLR 0.03533
GOTERM_BP_FAT GO:0006694 Steroid biosynthetic process HMGCR, FDPS, LSS, SC4MOL, DHCR24 0.04625
SP_PIR_KEYWORDS   Lipid transport APOB, APOA1, VLDLR 0.10992
  1. a GOTERM_BP GO term under the biological process category, GOTERM_CC GO term under the cellular component category, SP_PIR_KEYWORDS annotation from the Swiss-Prot and Protein Information Resource databases