Fig. 9
From: Identifying binary protein-protein interactions from affinity purification mass spectrometry data
Induced binary interaction network. a The method of determining cutoff. Interactions are ranked by their BINM scores. Different values of cutoff are used to predict binary interactions, and the corresponding F 2 scores are calculated using these predictions. Then we use the value that produces the largest F 2 score to construct binary network. For the Collins dataset, we use a cutoff of 2562; for the Friedel dataset, we use a cutoff of 3018. b Overlap between co-complex interactions in the Collins and Friedel datasets. c Overlap between the direct physical interactions identified by BINM from the Collins and Friedel datasets