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Table 2 Single nucleotide polymorphisms (SNPs) between TCH1516/FPR3757 and UAS391. Consensus base represents TCH1516 and FPR3757, allele represents a corresponding base in UAS391. Predicted amino acid changes in UAS391 compared to TCH1516 and FPR3757 were not displayed for synonymous SNPs

From: Fatty acid kinase A is an important determinant of biofilm formation in Staphylococcus aureus USA300

Consensus base (TCH1516/FPR3757) Allele UAS391 Gene locus tag (in TCH1516/FPR3757) Predicted amino acid change (TCH1516/FPR3757) Gene and putative function
G T USA300HOU_0286/SAUSA300_0267 Leu1Phe IS1272 transposase
T C USA300HOU_0155/SAUSA300_0145   Phosphate-import protein PhnD/ABC Transporter, periplasmic binding protein
G A USA300HOU_0521/SAUSA300_0513 Met386Ile gtlX: glutamyl-tRNA synthetase
A C USA300HOU_1051/SAUSA300_1013 Asn267Thr/Asn263Thr Bacterial cell division membrane protein FtsW
A G USA300HOU_1162/SAUSA300_1119 Glu524Gly fakA: Fatty acid kinase
G T USA300HOU_1166/SAUSA300_1123 Gly169Val fabD: malonyl CoA-acyl carrier protein transacylase (Lipid metabolism)
A G USA300HOU_1372/SAUSA300_1327 Val1114Ala Ebh: Cell Wall-Associated Fibronectin-Binding Protein
C A USA300HOU_2197/SAUSA300_2161   Hyaluronate lyase is a glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
G A USA300HOU_2631/SAUSA300_2566 Pro27Ser HTH-type Transcriptional regulator ArcR, signal transduction system
C T USA300HOU_2641/SAUSA300_2576   PTS system, fructose-specific II ABC component, multi protein system involved in regulation of metabolic and transcriptional process
T C USA300HOU_2319/SAUSA300_2285   Aldose 1-epimerase
G A USA300HOU_2602/SAUSA300_2542 Arg517* 1 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases (Lipid metabolism)
A C USA300HOU_2654/SAUSA300_2589 Ser1782Ala Serine-rich adhesin for platelets, cell surface protein precursor; KxYKxGKxW signal peptide
C T USA300HOU_0502/SAUSA300_0486 Thr85Met Uncharacterized protein YabR
C T USA300HOU_1626/SAUSA300_1585 Ser35Leu tRNA threonylcarbamoyladenosine dehydratase (Cells lacking this gene have a normal growth phenotype, but are unable to survive in a competitive growth situation with the wild-type strain. They display only the t6A but not the ct6A modification in tRNAs, and have lower decoding efficiency than wild-type. They show no defects in antibiotic sensitivity. In growth competition experiments, a tcdA mutant shows reduced fitness compared to wild-type, but outcompetes a csdA mutant.)
A G USA300HOU_2026/SAUSA300_1984 Lys118Arg Putative membrane peptidase YdiL
T C USA300HOU_1488/SAUSA300_1436   phage lipoprotein
T - USA300HOU_1338/SAUSA300_1298 Phe130fs2 5-bromo-4-chloroindolyl phosphate hydrolysis protein
  1. 1The symbol (*) refers to the predicted amino acid change as a stopcodon caused by the corresponding SNP
  2. 2The abbreviation (fs) refers to ‘frame shift mutation’