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Fig. 7 | BMC Genomics

Fig. 7

From: Complexity of a small non-protein coding sequence in chromosomal region 22q11.2: presence of specialized DNA secondary structures and RNA exon/intron motifs

Fig. 7

a Intron sequence alignment of protein genes, translocation breakpoint flanking sequence, the 10,000 bp unit and chimpanzee homologous region. Genomic positions of human and chimpanzee sequences are shown and are the reverse complement. Protein genes are shown in NCBI Gene Bank website: (http://www.ncbi.nlm.nih.gov/). TMC, transmembrane channel-like 1 , RefSeqGene on chromosome 9; RYR1, ryanodine receptor 1 (skeletal) (RYR1), RefSeqGene on chromosome 19; TAF7L, TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50 kDa, RefSeqGene on chromosome X; TSFM, Ts.translation elongation factor, mitochondrial (TSFM), RefSeqGene on chromosome 12; SRY, (sex determining region Y)-box 5 (SOX5), RefSeqGene on chromosome 12; ANK2, ankyrin 2, neuronal (ANK2), RefSeqGene (LRG_327) on chromosome 4. Sequence alignment is by Clustal W2 (www.ebi.ac.uk/Tools/msa/clustalw2/). b Percent identities

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BMC Genomics

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