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Table 2 Strain-specific gene content based on the comparison of the draft genomes of C. diphtheriae strains ISS 3319, ISS 4060, ISS 4746 and ISS 4749

From: Adherence and invasive properties of Corynebacterium diphtheriae strains correlates with the predicted membrane-associated and secreted proteome

Protein annotation

ISS 3319

ISS 4060

ISS 4746

ISS 4749

ISS 4746 – ISS 4749a

Hypothetical

69

73

22

10

86

Fimbrial & membrane

4

4

-

2

12

Transposase

6

13

3

1

14

Othersb

24

31

5

2

37

  1. aStrains ISS 4746 and ISS 4749 belong to the same ST, ST32. Hence, the genes shared by them but not with ISS 3319 and ISS 4060 were treated as strain-specific and these are detailed in the column “ISS 4746 – ISS 4749”
  2. bCDS encoding transcription regulators, components of restriction-modification systems or other cellular and metabolic activities were grouped within the ‘Others’ category