A comprehensive mapping of the structure and gene organisation in the sheep MHC class I region

BMC Genomics

Table 6 MHC class 1-like genes predicted from genomic BAC sequences published by Gao et al. (2010)

Name	#	S	Location	#Ex	AA len	SP	♋1/♋2	♋3	TM	C-Term	Type	Homologue
FJ985864rc_C1a	1	+	53040–56369	8	364	1-25	26–203	207–299	310–331	336–363	Ia	NP_001124406
FJ985864rc_C1b	2	+	97997–113333	5^a	229	No	27–93	95–186	194 215	No		NP_001124406
FJ985864rc_C1c	3	+	130285–133430	7	346	1–22	23–200	205–296	304–325	329–346^b	Ib	NP_001124406
FJ985870_C1a	1	+	26626–30134	8	364	1–25	26–203	207–299	310–331	336–363	Ia	NP_001124406
FJ985870_C1b	2	+	71762–87098	5^a	229	No	27-93	95-186	194 215	No		NP_001124406
FJ985870_C1c	3	+	104051–107196	7	346	1–22	23–200	205–296	304–325	329–346^b	Ib	NP_001124406
FJ985875rc_C1a	4	-	127171–130033	7	354	1–25	26–203	207–299	307 –329	332–354	Ib	NP_001035644
FJ985875rc_C1b	5	-	160117–162943	6	337	1–25	26–187	189–233	242–262	267–279^b	Ib	NP_001035644
FJ985859rc_C1a	6	-	1806–4642	7	356	1–25	26–203	207–299	308 327	332–356^b	Ib	CAI43976
FJ985859rc_C1b	7	-	28878–34806	7	355	1-18	28-204	208-300	309 329	333–355	Ib	NP_001124406
FJ985859rc_C1c	8	-	148998-151240	5	356	1–25	52–229	233–325	333 350	No		AAZ74696
FJ985874C1a	8	-	6993-9231	5	355	1–24	51–228	232–324	332 349	No		AAZ74696
FJ985874C1b^c	9	-	34484-37396	8	360	1–22	23–200	204–296	305 328	331–359	Ib	FJ985864rc_C1a
FJ985874C1b2^c	9	-	34390-37396	7	383	1–22	23–200	204–296	305 328	331–359	Ib	CAI43976
FJ985874C1c	10	-	77708-81297	7	379	1–25	26–203	207-299	305 328	333–355^b	Ib	NP_998933
FJ985874C1d	11	-	96704-100257	7	374	1–24	50–228	232–324	333–353	358–374^b	Ib	NP_001070451

S: strand. #: Locus number in telomeric to centromeric direction. #Ex: number of exons identified. AA len: Length of predicted amino acid sequence. SP: signal peptide. α1: alpha 1 domain. α2: alpha 2 domain. α3: alpha 3 domain. TM: transmembrane domain. C-Term: C-terminus end. Homologue indicates sequence used as homologous protein sequence with FGENESH+
^aTerminal exon not predicted. ^bWeak match. ^cAlternative transcript predictions

ISSN: 1471-2164