Fig. 1

Workflow for creating focus networks. Workflow of viPEr in creating focus networks between two nodes/two groups of nodes, or in exploring the neighborhood of a single node of interest. The user must select two nodes or group of nodes for creating a focus network. A single node is selected when exploring the neighborhood. Numerical data (for instance from an expression screen) must be added to the network for scoring paths of a focus network and for creating a neighbor focus network from a single node. In both cases, the user selects the search depth. After creating the focus network, the network can for instance be explored by using and visualizing GO-terms. PEANuT is used to find and visualize enriched pathways