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Fig. 2 | BMC Genomics

Fig. 2

From: Virtual pathway explorer (viPEr) and pathway enrichment analysis tool (PEANuT): creating and analyzing focus networks to identify cross-talk between molecules and pathways

Fig. 2

Focus networks between the primary atorvastatin target HMGCR and the transcription factors FoxA1, A2 and A3 of patient 65. Time course of patient 65 is shown at 6 h (a), 12 h (b), 24 h (c), 48 h (d) and 72 h (e). The focus networks were created using viPEr, with a maximal path length of 2 without considering the log2fold change: this allows direct comparison of time-course data. Up regulated nodes are shown as upward triangles, colored in red. Down regulated nodes are displayed as downward arrows, colored green. The Fox transcription factors are colored orange, as is the HMGCR. Protein-protein interactions have grey edges; edges of transcription factor gene interactions are colored red

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BMC Genomics

ISSN: 1471-2164

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