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Table 3 Peritrophic matrix-associated transcripts differentially expressed after IVM ingestion

From: Age and prior blood feeding of Anopheles gambiae influences their susceptibility and gene expression patterns to ivermectin-containing blood meals

Gene ID

Description

2IVM:2BF FC

6IVM:6BF FC

AGAP000570

salivary or midgut protein

37.57

18.30

AGAP002643

No description

21.93

7.95

AGAP006400

Alkaline phosphatase 2

21.74

5.85

AGAP001819

Predicted PM protein, Dinglasan et al. 2009 [97] (AgAper25b)

20.03

12.60

AGAP008648

No description

18.65

15.74

AGAP002848

Niemann-Pick Type C-2

16.83

11.92

AGAP007745

No description

15.46

7.79

AGAP006795

Chitin-binding peritrophin (AgAper1)

12.74

6.91

AGAP006432

ICHIT (AgChitinase)

9.75

3.13

AGAP006414

chitinase

7.80

4.64

AGAP001199

serine protease

7.12

5.70

AGAP009830

predicted PM protein, Dinglasan et al. 2009 [97] (AgAper14)

6.84

11.36

AGAP003713

No description

6.23

11.06

AGAP010056

hexosaminidase

4.84

3.32

AGAP006398

No description

3.94

3.38

AGAP006442

No description

2.63

4.35

AGAP004918

fibrinogen

2.51

2.33

AGAP006102

PRS1 (ribose phosphate diphosphokinase subunit), parital ( An. gambiae )

2.45

2.90

AGAP001193

No description

2.26

3.13

AGAP011630

No description

2.16

2.28

AGAP008487

sphingomyelin phosphdiesterase ( An. darlingi )

2.06

5.38

AGAP010733

Vanin-like protein 1

2.05

2.20

AGAP004809

protease m1 zinc metalloprotease

21.09

-

AGAP011302

alkaline phosphatase

12.51

-

AGAP010383

Solute carrier family 15 member 1

9.20

-

AGAP008370

carboxypeptidase A

7.91

-

AGAP011305

alkaline phosphatase

5.32

-

AGAP011453

transferrin ( An. darlingi )

5.19

-

AGAP004860

protease m1 zinc metalloprotease

4.83

-

AGAP006434

Predicted PM protein, Dinglasan et al. 2009 [ 97 ] (AgAper57)

4.46

-

AGAP006433

Predicted PM protein, Dinglasan et al. 2009 [ 97 ] (AgAper34)

3.34

-

AGAP008861

female reproductive tract protease GLEANR_896

3.08

-

AGAP006709

Chymotrypsin-1

−4.23

-

AGAP007142

Serine-type enodpeptidase

-

15.35

AGAP005065

loosely serine-type endopeptidase ( Aedes aegypti )

-

13.64

AGAP010383

Solute carrier family 15 member 1

-

10.06

AGAP006385

protease or trypsin (late or precurser)

-

9.29

AGAP008292

Trypsin-4

-

3.47

AGAP008294

Trypsin-3

-

2.94

AGAP006796

peritrophin (Aper9)

-

2.87

AGAP001198

chymotrypsin

-

2.46

AGAP004142

aspartate aminotransferase, cytoplasmic

-

2.18

AGAP006416

Serine protease SP24D

-

2.14

AGAP004883

No description

-

2.04

AGAP008295

Trypsin-2

-

−4.17

  1. Peritrophic matrix associated transcripts significantly differentially expressed following IVM ingestion. Inclusion based on identification of PM proteins by Dinglasan et al. [97], in which the An. gambiae adult proteome was thoroughly characterized by mass spectrometry, identifying a total of 209 proteins. Except those indicated as Dinglasan et al., descriptions were provided by VectorBase and descriptions in bold data were annotated based on BLASTp results (e-value ≤ 10−3) (Additional file 10)