Skip to main content

Table 3 Peritrophic matrix-associated transcripts differentially expressed after IVM ingestion

From: Age and prior blood feeding of Anopheles gambiae influences their susceptibility and gene expression patterns to ivermectin-containing blood meals

Gene ID Description 2IVM:2BF FC 6IVM:6BF FC
AGAP000570 salivary or midgut protein 37.57 18.30
AGAP002643 No description 21.93 7.95
AGAP006400 Alkaline phosphatase 2 21.74 5.85
AGAP001819 Predicted PM protein, Dinglasan et al. 2009 [97] (AgAper25b) 20.03 12.60
AGAP008648 No description 18.65 15.74
AGAP002848 Niemann-Pick Type C-2 16.83 11.92
AGAP007745 No description 15.46 7.79
AGAP006795 Chitin-binding peritrophin (AgAper1) 12.74 6.91
AGAP006432 ICHIT (AgChitinase) 9.75 3.13
AGAP006414 chitinase 7.80 4.64
AGAP001199 serine protease 7.12 5.70
AGAP009830 predicted PM protein, Dinglasan et al. 2009 [97] (AgAper14) 6.84 11.36
AGAP003713 No description 6.23 11.06
AGAP010056 hexosaminidase 4.84 3.32
AGAP006398 No description 3.94 3.38
AGAP006442 No description 2.63 4.35
AGAP004918 fibrinogen 2.51 2.33
AGAP006102 PRS1 (ribose phosphate diphosphokinase subunit), parital ( An. gambiae ) 2.45 2.90
AGAP001193 No description 2.26 3.13
AGAP011630 No description 2.16 2.28
AGAP008487 sphingomyelin phosphdiesterase ( An. darlingi ) 2.06 5.38
AGAP010733 Vanin-like protein 1 2.05 2.20
AGAP004809 protease m1 zinc metalloprotease 21.09 -
AGAP011302 alkaline phosphatase 12.51 -
AGAP010383 Solute carrier family 15 member 1 9.20 -
AGAP008370 carboxypeptidase A 7.91 -
AGAP011305 alkaline phosphatase 5.32 -
AGAP011453 transferrin ( An. darlingi ) 5.19 -
AGAP004860 protease m1 zinc metalloprotease 4.83 -
AGAP006434 Predicted PM protein, Dinglasan et al. 2009 [ 97 ] (AgAper57) 4.46 -
AGAP006433 Predicted PM protein, Dinglasan et al. 2009 [ 97 ] (AgAper34) 3.34 -
AGAP008861 female reproductive tract protease GLEANR_896 3.08 -
AGAP006709 Chymotrypsin-1 −4.23 -
AGAP007142 Serine-type enodpeptidase - 15.35
AGAP005065 loosely serine-type endopeptidase ( Aedes aegypti ) - 13.64
AGAP010383 Solute carrier family 15 member 1 - 10.06
AGAP006385 protease or trypsin (late or precurser) - 9.29
AGAP008292 Trypsin-4 - 3.47
AGAP008294 Trypsin-3 - 2.94
AGAP006796 peritrophin (Aper9) - 2.87
AGAP001198 chymotrypsin - 2.46
AGAP004142 aspartate aminotransferase, cytoplasmic - 2.18
AGAP006416 Serine protease SP24D - 2.14
AGAP004883 No description - 2.04
AGAP008295 Trypsin-2 - −4.17
  1. Peritrophic matrix associated transcripts significantly differentially expressed following IVM ingestion. Inclusion based on identification of PM proteins by Dinglasan et al. [97], in which the An. gambiae adult proteome was thoroughly characterized by mass spectrometry, identifying a total of 209 proteins. Except those indicated as Dinglasan et al., descriptions were provided by VectorBase and descriptions in bold data were annotated based on BLASTp results (e-value ≤ 10−3) (Additional file 10)