Table 2 Gene Ontology analysis of genes down-regulated in response to DHA in P. falciparum K1 trophozoites from RNA-seq analysis
Term | Count | List Total | Pop Hits | Pop Total | PValue | FDR |
|---|---|---|---|---|---|---|
GO:0005829 ~ cytosol | 70 | 276 | 85 | 963 | 3.4E–26 | 4.2E–23 |
GO:0044445 ~ cytosolic part | 54 | 276 | 62 | 963 | 4.6E–22 | 5.8E–19 |
GO:0006412 ~ translation | 99 | 348 | 181 | 1139 | 3.1E–13 | 4.5E–10 |
GO:0005840 ~ ribosome | 68 | 276 | 117 | 963 | 3.1E–12 | 3.8E–09 |
GO:0003735 ~ structural constituent of ribosome | 62 | 407 | 101 | 1385 | 1.4E–11 | 2.0E–08 |
GO:0022627 ~ cytosolic small ribosomal subunit | 22 | 276 | 22 | 963 | 3.5E–11 | 4.3E–08 |
GO:0030529 ~ ribonucleoprotein complex | 82 | 276 | 159 | 963 | 4.5E–11 | 5.6E–08 |
GO:0043228 ~ non-membrane-bounded organelle | 87 | 276 | 186 | 963 | 7.1E–09 | 8.9E–06 |
GO:0005198 ~ structural molecule activity | 65 | 407 | 120 | 1385 | 6.6E–09 | 9.3E–06 |
GO:0015935 ~ small ribosomal subunit | 25 | 276 | 35 | 963 | 6.5E–07 | 8.1E–04 |
GO:0000502 ~ proteasome complex | 20 | 276 | 30 | 963 | 5.9E–05 | 7.4E–02 |
GO:0044265 ~ cellular macromolecule catabolic process | 29 | 348 | 55 | 1139 | 9.2E–04 | 1.3E + 00 |