Table 2 Genes involved in nitrogen metabolism that are differentially expressed during nitrogen limitation in M. smegmatis mc2155
From: Defining the nitrogen regulated transcriptome of Mycobacterium smegmatis using continuous culture
Metabolic pathway | mc2155 locusa | Expression ratiob | FDRc | Description |
|---|---|---|---|---|
Amino acids | msmeg_2526 | 8.68 | 7.15E-35 | tyramine oxidase |
| Â | msmeg_3993 | 5.19 | 3.03E-14 | Asp/Glu racemase |
| Â | msmeg_0567 | 4.89 | 2.27E-12 | selenophosphate synthetase |
| Â | msmeg_3973 | 3.85 | 3.71E-05 | N-methylhydantoinase |
| Â | msmeg_4459d | 3.22 | 1.59E-03 | agmatinase |
| Â | msmeg_3317 | 3.06 | 1.59E-08 | dihydrodipicolinate reductase N-terminal domain-containing protein |
| Â | msmeg_6261 | 2.73 | 4.86E-04 | glutamine amidotransferase |
| Â | msmeg_6260 | 2.63 | 1.54E-04 | glutamine synthetase |
| Â | msmeg_2493 | 2.42 | 3.78E-03 | aminotransferase class I and class II family protein |
| Â | msmeg_6197d | 2.40 | 1.58E-02 | diaminopimelate decarboxylase |
| Â | msmeg_2494 | 2.20 | 8.20E-03 | Xaa-Pro aminopeptidase |
| Â | msmeg_5374 | 2.18 | 4.69E-05 | glutamate-ammonia ligase |
| Â | msmeg_6263 | 2.07 | 1.21E-02 | glutamate synthase |
| Â | msmeg_2100d | 2.02 | 9.01E-03 | peptidase M20/M25/M40 |
| Â | msmeg_6256d | 0.49 | 7.47E-06 | aspartate-semialdehyde dehydrogenase |
| Â | msmeg_5612d | 0.40 | 1.25E-07 | amino acid acetyltransferase |
| Â | msmeg_2691d | 0.40 | 6.92E-03 | N-acetylglutamate synthase |
| Â | msmeg_1762d | 0.32 | 4.60E-07 | piperideine-6-carboxylic acid dehydrogenase |
| Â | msmeg_5454d | 0.28 | 7.84E-08 | choloylglycine hydrolase |
| Â | msmeg_5119d | 0.25 | 5.76E-09 | 1-pyrroline-5-carboxylate dehydrogenase |
| Â | msmeg_0019d | 0.21 | 5.06E-23 | amino acid adenylation protein |
| Â | msmeg_5117d | 0.19 | 5.23E-07 | proline dehydrogenase |
| Â | msmeg_1414d | 0.19 | 5.97E-03 | amidinotransferase |
| Â | msmeg_1413d | 0.18 | 1.92E-05 | ornithine-oxo-acid transaminase |
| Â | msmeg_0022d | 0.18 | 3.49E-28 | L-ornithine 5-monooxygenase |
| Â | msmeg_0021d | 0.18 | 1.83E-21 | aspartate alpha-decarboxylase |
| Â | msmeg_1764d | 0.13 | 1.45E-03 | L-lysine aminotransferase |
Nucleotides | msmeg_4012 | 9.42 | 1.31E-24 | phenylhydantoinase |
| Â | msmeg_5729 | 7.24 | 5.08E-19 | hydantoin racemase |
| Â | msmeg_1294 | 3.89 | 2.39E-17 | OHCU decarboxylase |
| Â | msmeg_1296 | 3.78 | 2.28E-07 | uricase |
| Â | msmeg_2748 | 3.69 | 1.44E-05 | soluble pyridine nucleotide transhydrogenase |
| Â | msmeg_1298 | 3.67 | 6.88E-12 | guanine deaminase |
| Â | msmeg_3996 | 3.53 | 3.56E-13 | phenylhydantoinase |
| Â | msmeg_1295 | 3.52 | 2.55E-12 | transthyretin |
| Â | msmeg_3553d | 2.95 | 1.98E-04 | phenylhydantoinase |
| Â | msmeg_6116 | 2.64 | 1.09E-08 | OHCU decarboxylase |
| Â | msmeg_3473 | 2.55 | 6.53E-03 | uracil phosphoribosyltransferase |
| Â | msmeg_5727 | 2.21 | 4.92E-06 | allantoicase |
Urea | msmeg_2187 | 3.33 | 5.04E-06 | urea amidolyase |
| Â | msmeg_1425d | 2.60 | 2.80E-08 | creatininase subfamily protein |
| Â | msmeg_3623 | 2.45 | 1.22E-06 | urease accesory protein UreG |
| Â | msmeg_0435d | 2.40 | 6.48E-06 | allophanate hydrolase subunit 2 |
| Â | msmeg_0436d | 2.17 | 1.19E-04 | allophanate hydrolase subunit 1 |
| Â | msmeg_2189 | 2.16 | 9.92E-03 | allophanate hydrolase |
| Â | msmeg_3624 | 2.11 | 1.40E-03 | urease accesory protein UreF |
|  | msmeg_3627 | 2.06 | 3.27E-04 | urease subunit γ |
C-N bond | msmeg_5358 | 7.23 | 9.62E-35 | acetamidase/formamidase |
| Â | msmeg_5359 | 4.64 | 6.37E-14 | cyanate hydratase |
| Â | msmeg_0571 | 4.06 | 1.08E-17 | carbon-nitrogen hydrolase |
| Â | msmeg_3995 | 3.99 | 1.09E-13 | N-carbamoyl-L-amino acid amidohydrolase |
|  | msmeg_6266 | 3.68 | 5.45E-18 | thiocyanate hydrolase subunit β |
| Â | msmeg_4367 | 3.67 | 2.87E-17 | formamidase |
|  | msmeg_6267 | 3.42 | 2.79E-15 | thiocyanate hydrolase subunit γ |
| Â | msmeg_0566 | 2.96 | 3.15E-06 | aliphatic amidase |
| Â | msmeg_4381 | 2.58 | 1.56E-08 | amidase |
| Â | msmeg_3403 | 2.38 | 2.83E-06 | formamidase |
| Â | msmeg_5373 | 2.35 | 1.43E-04 | nitrilase 2 |
| Â | msmeg_0443d | 2.28 | 1.82E-02 | carbon-nitrogen hydrolase |
| Â | msmeg_3397 | 2.26 | 3.75E-04 | acetylornithine deacetylase |
| Â | msmeg_2491 | 2.25 | 3.45E-02 | acetylornithine deacetylase |
Nitrate/Nitrite | msmeg_0427 | 4.42 | 1.52E-03 | nitrite reductase, large subunit |
| Â | msmeg_0332d | 0.16 | 7.18E-10 | 2-nitropropane dioxygenase |
CoA biosynthesis | msmeg_6097d | 0.49 | 9.14E-05 | pantoate-β-alanine ligase |