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Table 3 Detection of differential expression by model and data set

From: On the relevance of technical variation due to building pools in microarray experiments

Number of

Data set

transcripts

Simulated

 

Experimental

 

identified

s1

s2

s3

 

Mouse

Rat

Human

 

m1 & m2

3112

3119

3128

 

3344

1636

787

 

m1

48

113

279

 

504

141

350

 

m2

4

13

29

 

516

12

154

 
  1. Number of transcripts identified as differentially expressed at an FDR of 5 % by data set and model. Simulated data sets s1, s2, and s3 refer to scenarios where none, one third, and all transcripts were associated with a non-zero blending error variance component. The number of transcripts identified with both models is indicated by m1 & m2, transcripts identified solely with the null model (m1) or the full model (m2) are shown in the second-to-last and the last line