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Table 1 The table shows the variant numbers identified by the different methods through the different filtering steps. Note, mean raw calls per mouse is not available for P4 as GATK calls jointly over all mice. Pass QC involves filtering for olfactory genes, known Sanger variants and PASS flag from GATK

From: Genome-wide analysis of chemically induced mutations in mouse in phenotype-driven screens

 

P1

P2

P3

P4

Mean raw calls

13,775,275

Mean raw calls

66,493

71,705

74,093

NA

per mouse

    

Total raw calls

145,484

131,926

124,788

54,698,903

(for 53 founders)

    

Mean filtered

39

44

41

66

SNVs per mouse

    

Mean combined

111

filtered SNVs

    

Mean agreeing

54

SNVs

    

Mean pass QC

21

Total ENU mutation

1281

(for 53 founders)