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Fig. 4 | BMC Genomics

Fig. 4

From: Relationship between gene expression and lung function in Idiopathic Interstitial Pneumonias

Fig. 4

Localization of rhotekin 2 expression in IPF lung of patients with mild (left panels) and severe (right panels) disease. Immunohistochemical staining of airways (a), honeycomb cysts (b), and alveolar cysts (c) lung tissue reveals some decrease in expression of rhotekin 2 in airway epithelial cells in patients with severe compared to mild disease accompanied by an increase in expression in hyperplastic alveolar type II cells in alveolar cysts. Top panels represent rhotekin 2 stained sections and bottom panels are corresponding tissue sections incubated with non-immune serum (negative primary antibody controls). Tissue sections were counterstained with hematoxylin. Images were taken at 10× and 40× (inset) magnifications

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