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Table 1 Summary of putative HI gene clusters (HIBGCs) identified in MAR4 strains. The PTases present in each HIBGC are indicated along with the annotation of key biosynthetic genes

From: Genomic insights into the evolution of hybrid isoprenoid biosynthetic gene clusters in the MAR4 marine streptomycete clade

Gene cluster PTC(s) present HIBGC content Product
nap PTC10, PTC6 Type III polyketide synthase, three haloperoxidases, mev pathway napyradiomycin
HIBGC1 PTC9 FabH-like protein, AvrD-like protein Unknown
HIBGC2 PTC13 haloperoxidase Unknown
HIBGC3 PTC2, PTC8, PTC11 squalene-hopene cyclase Unknown
HIBGC4 PTC2, PTC12 squalene-hopene cyclase Unknown
HIBGC5 PTC8, PTC11 Found on very short contig, additional genes in this cluster may exist Unknown
HIBGC6 PTC4 isopentenyl pyrophosphate synthase Unknown
HIBGC7 PTC3 polyprenyl synthase Unknown
HIBGC8 PTC7 three haloperoxidases; found on very short contig, additional genes in this cluster may exist Unknown
HIBGC9 PTC7, PTC5 Two type III polyketide synthases; portion of this HIBGC is identical to HIBGC8 marinonea
HIBGC10 N/A indole PTase, phytoene synthase Unknown
HIBGC11 PTC1 full suite of phenazine biosynthesis genes (phzABCDEFG) lavanducyanina
HIBGC12 PTC2 squalene-hopene cyclase Unknown
  1. aPredicted
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