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Table 1 Summary of TUV86-2 colonization QTLs in ARI BXD micea

From: Mapping of genetic loci that modulate differential colonization by Escherichia coli O157:H7 TUV86-2 in advanced recombinant inbred BXD mice

Name of mapped trait (Phenotype)

Chr (mm9b)

Peak LRS

Genetic marker(s) associated with peak locus

Location of genetic markers (Mb)

Colonization one day after infection

9

20.19c

gnf09.010.169, rs13480073, and mCV24962297

13.23–15.69

14

13.84

rs13482392, gnf14.114.290, rs13482396

118.97–119.71

Colonization two days after infection

9

16.12

gnf09.010.169

13.23–25.69

14

12.09

rs13482396, gnf14.085.610 and rs3707842

91.32–120.03

Colonization four days after infection

9

12.29

gnf09.010.169, rs13480073, mCV24962297

13.23–25.69

Difference in colonization between day two and one after infection

13

12.05

rs6209128 and rs3023086

52.86–53.52

Difference in colonization between day three and one after infection

7

13.36

rs6206014

47.86

18

11.98

rs3718618 and rs3669949

69.37–69.9

19

12.99

rs13483513, gnf19.005.316, rs4232041 and rs4232042

3.41–10.15

Difference in colonization between day four and one after infection

5

12.86

rs13478413 and rs3688859

98.23–100.05

17

11.6

rs13483110

76.56

Difference in colonization between day three and two after infection

4

15.52

rs3719891–rs6358921

140.88–150.45

10

12.04

rs13459120, rs13480580

35.75–36.17

15

12.02

rs4230714–rs3701428

44.2–55.00

Difference in colonization between day four and two after infection

1

11.66

rs13475818 and UT_1_38.719268

38.07

15

11.28

rs3717268 and rs13482709

90.7–91.5

X

16.64

rs13483746, rs13483748 and rs13483736

44.68–48.08

Difference in colonization between day four and three after infection

12

11.17

rs13481566–rs13481579

85.87–89.93

Overall strain specific variation in pattern of colonization across BXD strains (Linear slopes of medians)

17

12.47

rs13483110

76.5

Overall strain specific variation in pattern of colonization across BXD strains (Polynomial slopes of medians)

X

12.17

rs13483770, gnfX.044.260, rs13483785, rs13483786

56.48–61.86

  1. aTrait linkage analysis done with 5000 permutation tests
  2. bmm9: NCBI Mouse Build 37
  3. cSignificant quantitative trait locus