Strainsa
| Allelesb
| EOPc
|
|---|
spr0290 | spr1130 | spr1445 | spr1453 | (Dp-1) |
|---|
R6 | WT | WT | WT | WT | 1 |
R6smR
| WT | WT | WT | WT | 1 |
R6-DP1R
| R | R | R | R | 10−8
|
R6spr1130
| WT | R | WT | WT | 10−8
|
R6spr1445
| WT | WT | R | WT | 1 |
R6-DP1R-spr1130WT
| R | WT | R | R | 1 |
-
aR6smR integrated an rpsL allele conferring resistance to streptomycin (smR). Each mutated and WT alleles presented in the table was co-transformed with this rpsL allele that was used as a surrogate marker for the selection of transformants (see Methods). Although not indicated, every transformants in Table 4 are smR
-
bWT, S. pneumoniae R6 WT gene sequence; R, S. pneumoniae R6-DP1R gene sequence
-
cEOP, efficiency of plaquing. Represents the ratio of phage titers from the test strain to the indicator strain R6 WT. Measured from three independent triplicate
