Fig. 1

Gene expression profiling of liver compensatory growth in zebrafish. a Schematic diagram of sham surgery and hepatectomy of the whole ventral lobe and materials collection in sham and experiment groups. DL: dorsal lobe, VL: ventral lobe, PH of VL: partial hepatectomy of the whole ventral lobe. Black box indicates the materials collected in correspondent groups. b Venn diagrams represent the number of differentially expressed genes during the liver compensatory growth. c Gene clustering based on gene expression profiles across the compensatory growth process. A total of 5652 genes are differentially expressed during this process. These genes were clustered into eight groups based on the similarity of their expression patterns during liver compensatory growth at 6-h time point and 24-h time point after removal of the ventral lobe. d Genes encoding growth factors/ligands and involved in angiogenesis or apoptosis were clustered based on their expression patterns at 6-h time point and 24-h time point after surgery. The gene name, gene symbol, and log2 fold change of each gene can be found in Additional file 1. The color chart indicating fold change of expression uses a base 2-logarithm scale. Red and green represent increased and decreased gene expression, respectively