Fig. 4

Heat map and hierarchical clustering of differentially expressed miRNAs. Neurotransmitter-responsive miRNAs were clustered with converted FPKM value by Cluster 3.0 in default settings. Converted expressions of certain miRNA were shown with different colors. The “+” or “-” symbol after each miRNA ID indicates its significance state of expression difference in PBS/ACh, PBS/NE, ACh/NE comparison with “+” represents significant difference and “-” represents no significant difference