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Table 1 Immune-related genes putatively targeted by NeurimmiRs

From: The comprehensive immunomodulation of NeurimmiRs in haemocytes of oyster Crassostrea gigas after acetylcholine and norepinephrine stimulation

Classification Target Gene Gene ID NCBI Accession Number miRNA miRNA Expression
Receptors carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) CGI_10010080 EKC30453 cgi-miR-242 ACh (+1)
  C-type mannose receptor 2 (MRC2) CGI_10013598 EKC36613 scaffold987_25421 ACh (+)
  Toll like receptor 1 (TLR1) CGI_10021136 EKC32484 scaffold43122_31369 ACh (+)
  multiple epidermal growth factor-like domains 10 (MEGF10) CGI_10022484 EKC30915 scaffold987_25421 ACh (+)
  CD63 antigen (CD63) CGI_10024556 EKC30322 scaffold444_16949 ACh (+)
  muscarinic acetylcholine receptor (mAChR) CGI_10026715 EKC38948 scaffold1535_2758 ACh (+)
  macrophage mannose receptor 1 (MRC1) CGI_10003643 EKC21607 scaffold659_26519 NE (+)
  nicotinic acetylcholine receptor (nAChR) CGI_10012300 EKC27791 cgi-miR-1989 NE (+)
Signaling molecules CREB-binding protein (CREBBP) CGI_10004570 EKC21118 scaffold987_25421 ACh (+)
  Ras-related protein Rab-21 (RAB-21) CGI_10012407 EKC30126 scaffold625_3183 ACh (−2)
  E3 ubiquitin-protein ligase mib2 (MIB2) CGI_10012437 EKC24345 scaffold987_25421 ACh (+)
  Ras-related protein Rab-5C (RAB-5C) CGI_10016941 EKC27651 scaffold987_25421 ACh (+)
  TNF receptor-associated factor 3 (TRAF3) CGI_10019401 EKC37852 scaffold365_16162 ACh (+)
  TNF alpha-induced protein 3 (TNFAIP3) CGI_10016154 EKC18030 cgi-miR-1989 NE (+)
  suppressor of G2 allele of SKP1 homolog (SUGT1) CGI_10016471 EKC33616 cgi-miR-184d NE (+)
Immune effector Catalase (CAT) CGI_10003354 EKC25821 scaffold987_25421 ACh (+)
  heat shock 70 kda (HSP70) CGI_10006158 - scaffold625_3183 ACh (−)
  interferon-induced protein 44 (IFI44) CGI_10011953 EKC23550 scaffold1121_5128 ACh (+)
  HSP70 CGI_10014234 - scaffold444_16949 ACh (+)
  HSP70 CGI_10014235 XP_011426978 scaffold444_16949 ACh (+)
  complement C1q-like protein 4 (C1qL4) CGI_10026904 EKC37620 scaffold105_17058 ACh (+)
  cytochrome p450 (P450) CGI_10011491 EKC33448 scaffold659_26519 NE (+)
  P450 CGI_10012275 EKC18482 cgi-miR-184a NE (+)
  HSP70 CGI_10027276 EKC43179 cgi-miR-184a NE (+)
  1. 1miRNA increased in corresponding group
  2. 2miRNA decreased in corresponding group