Fig. 8

Co-occurrence network of resistance genes on plasmids. The network was built based on the observed co-occurrence pattern of BMRGs with ARGs on 4582 plasmids. The network was filtered such that only connections between BMRGs and ARGs, and between integrases/transposases and resistance genes were kept if the connected genes occurred together on at least 10 plasmids. No connections are shown between ARGs to better emphasize the co-selection potentials. The thickness of each connection (edge) between two resistance genes (nodes) is proportional to the number of times the two resistance genes co-occurred on the same plasmids