Table 1 Phenotypes of 10 weeks old males and females of reciprocal crosses between BFMI and B6N with and without cross-fostering on high fat diet
From: The direction of cross affects obesity after puberty in male but not female offspring
Phenotypes1 | F1(BFMI x B6N) | F1(B6N x BFMI) | p-Value for direction-of-cross effect | |||
|---|---|---|---|---|---|---|
BFMI father (patBFMI) | BFMI mother (matBFMI) | |||||
Males | Females | Males | Females | Males | Females | |
Maternal fostering | ||||||
Body mass (g) | 34.23 (3.26) | 26.16 (2.02) | 36.82 (3.96) | 25.27 (2.06) | n.s. | n.s. |
Fat mass (g) | 3.86 (1.49) | 3.34 (1.01) | 7.06 (2.56) | 3.44 (1.04) | 0.0037 | n.s. |
Lean mass (g) | 27.54 (2.06) | 20.45 (1.00) | 26.93 (2.10) | 19.68 (1.09) | 0.0536 | 0.0855 |
Fat / Lean mass ratio | 0.14 (0.05) | 0.16 (0.04) | 0.26 (0.08) | 0.17 (0.05) | 0.0009 | n.s. |
Liver mass (g) | 1.55 (0.23) | 1.21 (0.10) | 1.68 (0.18) | 1.16 (0.12) | n.s. | n.s. |
Liver triglycerides/ protein (μg/μg) | 0.45 (0.09) | 0.47 (0.11) | 0.59 (0.22) | 0.45 (0.08) | 0.0843 | n.s. |
Blood glucose levels (mg/dl) | 165.33 (27.20) | 135.92 (12.22) | 174.25 (23.80) | 133.25 (10.71) | n.s. | n.s. |
Cross-fostering | ||||||
Body mass (g) | 34.27 (3.41) | 25.96 (3.75) | 35.63 (2.65) | 24.36 (1.71) | n.s. | n.s. |
Fat mass (g) | 4.06 (2.06) | 3.45 (1.56) | 5.54 (1.74) * | 2.70 (0.99) | 0.0142 | n.s. |
Lean mass (g) | 29.54 (1.84) ** | 21.69 (3.06) | 29.61 (1.68) ** | 20.64 (1.19) ° | n.s. | n.s. |
Fat / Lean mass ratio | 0.14 (0.06) | 0.16 (0.07) | 0.19 (0.06) ** | 0.13 (0.04) ° | 0.0067 | n.s. |
Liver mass (g) | 1.66 (0.21) | 1.22 (0.23) | 1.75 (0.15) | 1.17 (0.13) | n.s. | n.s. |
Liver triglycerides/ protein (μg/μg) | 0.15 (0.09)** | 0.34 (0.17)° | 0.21 (0.08)** | 0.26 (0.13)** | 0.0307 | n.s. |
Blood glucose levels (mg/dl) | 137.82 (19.07) ** | 130.36 (13.13) | 151.83 (22.7) * | 139.29 (20.64) | 0.0307 | n.s. |