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Table 4 Differentially expressed genes between patBFMI and matBFMI on X chromosome and mitochondria

From: The direction of cross affects obesity after puberty in male but not female offspring

Gene Symbol1 Chr Gene Description (mgi) Mean RPKM2 Fch matBFMI/
patBFMI
tTest F1 TFBS3
patBFMI matBFMI
Trmt2b X TRM2 tRNA methyltransferase 2B 2.07 1.83 0.88 0.0008 -
Ssr4 X signal sequence receptor, delta 3.01 2.84 0.94 0.0013 -
Rps4x X ribosomal protein S4, X-linked 4.3 4.17 0.97 0.0026 -
Prdx4 X peroxiredoxin 4 3.63 3.49 0.96 0.0086 -
Shroom2 X shroom family member 2 1.66 1.46 0.88 0.0163 -
Rps24-ps3 X ribosomal protein S24, pseudogene 3 5.17 5.04 0.97 0.0212 -
Gm5763 X predicted pseudogene 5763 0.85 1.52 1.79 0.0255 -
Nsdhl X NAD(P) dependent steroid dehydrogenase-like 3.15 3.47 1.10 0.0331 -
Abcd1 X ATP-binding cassette, sub-family D (ALD), 1 1.37 1.67 1.22 0.0439 -
Mospd2 X motile sperm domain containing 2 1.92 1.88 0.98 0.0456 -
Haus7 X HAUS augmin-like complex, subunit 7 1.85 2.23 1.21 0.0486 Esrrb
Cd99l2 X CD99 antigen-like 2 1.77 1.87 1.06 0.0489 Esrra,Esrrb
Serpina7 X serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 2.01 2.52 1.25 0.0508 ERE
Pls3 X plastin 3 (T-isoform) 2.84 2.74 0.96 0.0557 -
Tsc22d3 X TSC22 domain family, member 3 3.59 3.20 0.89 0.0667 ADR3
Slc16a2 X solute carrier family 16 (monocarboxylic acid transporters), member 2 2.77 2.62 0.95 0.0668 -
Ar X androgen receptor 0.26 0.62 2.38 0.0678 -
Hsd17b10 X hydroxysteroid (17-beta) dehydrogenase 10 4.21 4.43 1.05 0.0688 -
Tmsb4x X thymosin, beta 4, X chromosome 3.8 3.63 0.96 0.0703 IR3
Gyk X glycerol kinase 2.9 2.97 1.02 0.0790 Esrra,Esrra, ERE
Gm14760 X predicted gene 14760 3.02 3.18 1.05 0.0803 Esrra,Esrrb
Wdr13 X WD repeat domain 13 1.62 1.7 1.05 0.0831 Esrra, ERE
Gm14373 X predicted gene 14373 2.49 2.41 0.97 0.0858 -
Cldn2 X claudin 2 3.22 3.45 1.07 0.0870 -
Rlim X ring finger protein, LIM domain interacting 2.2 2.12 0.96 0.0910 -
Zfx X zinc finger protein X-linked 1.47 1.23 0.84 0.0915 -
Pqbp1 X polyglutamine binding protein 1 2.53 2.70 1.07 0.0971 -
Lamp2 X lysosomal-associated membrane protein 2 4.14 4.01 0.97 0.0974 Esrra,Esrrb
F8 X coagulation factor VIII 1.99 1.83 0.92 0.0979 -
Gm6472 X predicted pseudogene 6472 4.99 4.90 0.98 0.0997 -
mt-Nd1 MT mitochondrially encoded NADH dehydrogenase 1 6.76 6.42 0.95 0.0165 -
  1. 1Bold gene symbols indicate up-regulation in matBFMI. Y chromosomal genes were not differentially expressed. Chr – chromosome, matBFMI – BFMI mother, patBFMI – BFMI father, Fch – fold-change
  2. 2All values were log-transformed (ln)
  3. 3TFBS - Transcription factor binding sites for steroid hormones. Esrrb – estrogen related receptor b, ERE – estrogen response element, ADR3 – androgen direct repeats of the hexameric half-site, IR3 – androgen inverted repeats of hexameric half-site separated by 3 bp of spacer